When Does the Michaelis−Menten Equation Hold for Fluctuating Enzymes?
نویسندگان
چکیده
منابع مشابه
When does the Michaelis-Menten equation hold for fluctuating enzymes?
Enzymes are dynamic entities: both their conformation and catalytic activity fluctuate over time. When such fluctuations are relatively fast, it is not surprising that the classical Michaelis-Menten (MM) relationship between the steady-state enzymatic velocity and the substrate concentration still holds. However, recent single-molecule experiments have shown that this is the case even for an en...
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ژورنال
عنوان ژورنال: The Journal of Physical Chemistry B
سال: 2006
ISSN: 1520-6106,1520-5207
DOI: 10.1021/jp065187g